Can imipramine cause nightmares
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Measure content performance. Develop and improve products. List of Partners vendors. If you have clinical depression, you're probably familiar with the wee hours of the morning. Depression is known to cause sleep disturbances such as insomnia, early morning awakenings, and bad dreams or nightmares. Specifically, depression decreases the length of time it takes to enter REM sleep called REM sleep latency and increases the frequency of rapid eye movements during sleep called REM sleep density.
Ironically, antidepressants, which treat depression, can also impact your dreams through affecting REM sleep. Research has shown that antidepressants may induce positive or negative dream emotions, influence how often you dream, and decrease your recall of dreams. In a report that was published in Sleep Medicine Reviews , Gotthard Tribl and his research team completed a systematic review that examined the impact of antidepressants on dream content in both depressed and non-depressed individuals.
Out of all the studies that had been published over a period of 60 years, they found a total of 21 clinical studies and 25 case reports that were eligible for review. The studies compared dream content across a spectrum of different antidepressants as well as making comparisons between the dream content of those taking or not taking an antidepressant.
What the study authors found was that taking antidepressants tends to make both depressed and non-depressed individuals remember their dreams less often. Tricyclics are older antidepressants that inhibit the reuptake of serotonin and norepinephrine. They include such medications as Elavil amitriptyline , Anafranil clomipramine , Tofranil imipramine , and Surmontil trimipramine. Antidepressants belonging to the SSRI class, as well as serotonin-norepinephrine reuptake inhibitors SNRIs , were found in the review to intensify dreams and increase how often people reported having nightmares.
Tricyclics, on the other hand, tended to produce more positive dreams while withdrawal of antidepressants usually caused an increase in dream recall and more frequent nightmares.
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